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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus:  I'm willing to try something.  You seem to have a lot of suggestions, what can i try?  I have found pre drinking helps a lot.  Once i am drunk and relxed it seems to pretty much go away.  IT IS a pain though.  Any other suggestions?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

is there anyway to establish some offical research for this? or any contacts someone can get in touch with? researchers need to know that there needs to be a cure.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

There is an offical research for asian flush in Japan. It is a private research center.  Please try to understand how much goes into researching. You have a lot of paper work with legal matters, research process, and have to deal with loss, tampered, and inaccurate data.  Some research takes countless meetings, and approval to do certain actions can take months and years.  To fund a research for asian flush takes millions of dollars, and countless hours of work.  There is a pill out in Japan that cost $4,000 dollars that buisness men use to surpress the asian flush.  I don't know how it works, and I don't know what extensive use of the pill can do, or do I know if your body will build a tolerance to the pill.
  To James: I realize how painful doing the pre drink is! I have talked and associated with a lot of asian flush individuals who feel the same fustrations. I also see how bad it makes one feel.  I have theories on how it is possible to over come the asian flush threw your body naturually adapting.  It might be a painful to achieve it.  My theories aren't fully developed yet.  To paint you a picture of my theory, it is like a 300ib person trying to loose 150ibs.  So it takes a lot of dedication.  I'am trying to think of ways of how to stop the irregular heart beat, which causes the flushing. Then you have the issue of the sick feeling.  To help point all of you in the right direction of how to take this on, without just trying any old thing. You might have to try self test to see what helps, then look at the basic make up of what caused your reaction to be less intense or what surpressed it for a while.  Take pepcid AC for example, it seems to work wonders for many who use it at the beggining.  A chemical in Pepcid AC is helping your body not to respond to alcohol in an extreme manner.  Some of the suggestions I listed were off the wall. So James allow me some time and I'll get back with you with better suggestions to help you out.  I will get back to you soon. James I also suggest you be a leader on this site, to help other individuals. If you do choose to be a leader, please tell me and I will explain what needs to be done.  So think on that and I'll swing by soon, I have to go now so good luck to all.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I tried that Pepcid AC experiment for the first time last nite.

-ate 30mg (I got scared to take more because the box said not to exceed 2 in 24hrs.)
-waited an hour before drinking
-I only had like 1/3 of a bottle of St. Ides- I'm a very small full blooded chinese girl (5'3" 115lbs.) so I was feeling pretty tipsy after that...perhaps the Pepcid helped initiate it quicker too.
-and it worked! no redness. perhaps a faint pink in my eyes, but nothing else.

HOWEVER, after that, I got super nauseous and puky for like an hour with super painful stomach cramps.
So what's up with that?! I did happen to start my period this morning, so could that have had an effect on me last nite? I don't think I drank too much? Please offer your thoughts. I very much enjoy this message board and everything people are saying.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus,
I have been drinking 1-3 beers a day on average for about 5 months now.  I probably flush a little less now than before, and another thing is that the flush goes away faster now than before, but it is not that much less intense.  2 beers fast will get me fairly red, but feeling ok, besides a slighltly faster heart rate.  I think the problem is that ADH adapts to ethanol together with the slow ALDH2, so the flush stays about the same, because the relative rates of metabolism are what is important (as in ADH/ALDH).  I also find that the flush is less if you havent slept in a day, not that this is a realistic solution at all.  I have also tried the fruit shake idea, although I have never tried drinking six shakes in order to get ready.  I will keep with the couple beers a day and see what happens.  Another problem for me at least, is that I think that I have both asian fast ADH and irish german high amounts of ADH, so I process ethanol faster than I would like.  On the other hand, speeding up the ALDH metabolism would be a much more desirable solution than slowing down ADH.  what are your ideas natifus

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

To Training: Your drinking daily is what some people have been doing to try beat the defect.  In some cases it was possible for the SYMPTOMS to go away. In this case it is very few people that are able not to have a recurrence.  You are probally processing alcohol faster, because your drinking habbit is similar to an alcoholic. Alcoholics process alcohol faster due to developing a second pathway to process alcohol in larger ammounts.  If you stopped drinking for about a month or two, it is most likely that you will have the old intense Asian Flush effects you had when you first drank. Not everyone has the same defective enzyme, some of your enzymes work faster than others.  Some of you are able to drink 2 beers before showing effects, and some of you can drink 1/8 of a beer and have instint effects. Some of your enzymes operate faster, but it is still in low ammounts compaired to the original enzyme.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus wrote:

There is a pill out in Japan that cost $4,000 dollars that buisness men use to surpress the asian flush.  I don't know how it works, and I don't know what extensive use of the pill can do, or do I know if your body will build a tolerance to the pill.

Do you have any more information about this pill?  i.e. what it is called, any related links?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

yeah, i tried this for the first time after reading about it on this website, this works amazingly well, can't believe it myself, I usually take 80mg (4 pills) before i go out for the night and don't have to worry about being beat red and have my asthma and lungs constrict anymore. its really amazing actually..

309

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus wrote:

To Training: Your drinking daily is what some people have been doing to try beat the defect.  In some cases it was possible for the SYMPTOMS to go away. In this case it is very few people that are able not to have a recurrence.  You are probally processing alcohol faster, because your drinking habbit is similar to an alcoholic. Alcoholics process alcohol faster due to developing a second pathway to process alcohol in larger ammounts.  If you stopped drinking for about a month or two, it is most likely that you will have the old intense Asian Flush effects you had when you first drank. Not everyone has the same defective enzyme, some of your enzymes work faster than others.  Some of you are able to drink 2 beers before showing effects, and some of you can drink 1/8 of a beer and have instint effects. Some of your enzymes operate faster, but it is still in low ammounts compaired to the original enzyme.

Natifus:

You seem to imply that you have some specialized research or that you have some scientific background training.  I'm curious as to where you got such detailed information to be able to "diagnose" people.  Are you an MD or PhD?

Please don't take this the wrong way, but I want to make sure that we're all trying to beat this thing, but doing so safely and not relying on "pseudo science" that could end up in a bad way.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus-
you say that there is a research program going on in Japan by a private lab for an acetaldehydemia cure.  do you have any more info on this, like a website?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Hello,

I don't know if I suffer from the same thing or if it is an allergic reaction to additives in the alcohol but all of my symptoms are the same.

I used to take Cetirizine Hydrochloride or Cetirizine di-hydrochloride (Pititeze)to suppress the symptoms because I thought it was an allergic reaction, however this pill no longer works so effectively for me.

I now use Loratidine which is another antihistamine and this works much better. Careful not to take too many though, never more than one pill in 24 hours.

Can someone with Asian Flush try taking a Loratidine an hour before drinking and let me know how it went. I am eager to know if my symptoms are caused by the same problem or by an allergic reaction.

Thanks

312

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I've tried Pepcid AC a while ago and it (almost) cured me of this wretched Asian Glow, I take 2 30-40 mins before drinking and it reduced the glow dramatically. But the problem is the cost, it's about €6 for 10 or something like that =/ I can't afford that everytime I go out...

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I've found a couple of websites in New Zealand that allow shipping overseas.
A rough price conversion would be NZ$1 = Euro$0.50 or US$0.50

In NZ its called Pepzan - it comes in boxes of 14 and each pill is 20mg

http://www.chemistshop.co.nz/
http://www.chemist.co.nz/

I've just placed an order myself and I look forward to getting some stuff soon!

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

how long does the flush/hives stay on your body? My face gets flushed but I don't sweat or anything. And then my body (torso area although sometimes spread to upper arms and thighs) gets blotchy hives but they don't itch. They just look freaky as hell. And then it takes SO LONG for them to go away - 1.5 to 2 weeks - NEVER sooner than that. I'm reading this stuff about the genes and what you all post and I just don't know if it's what I have. I don't feel ill ever, my body just breaks out. Is this just an allergy as opposed to a genetic issue? And should I stop drinking if it's an allergy because it could get bad one day? It freaks me out a little. And I'm not talking about drinking a ton, I very very rarely have more than 2 drinks in one day, usually only one. My drinking habits are - I drink about half a glass of wine every other night with dinner and this doesn't cause the hives. But on average once a week I go out to a bar and have one drink and ALWAYS get the hives. So now I ask the bartenders to go light on the alcohol and don't always finish my drinks but still get the hives when I go out. And if I have more than half a glass of wine I'll get the hives too. So basically I get hives every time I drink except for when I have the half a glass of wine with dinner. I have a decent number of asian friends and while many of them get the intense flushing - all their symptoms go away by the next morning - I even have one friend who gets the same body blotchiness I do but not for more than a night.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I've been experimenting with Pepcid AC and red wine.  The results were disappointing.  :::sigh:::   While the Pepcid seemed to delay the onset of the flush by around twenty minutes, the glow eventually hit me.  Once again, I was fire-engine red with that freaky shine coming off my skin and eyes.

I tried the Pepcid AC twice.  First time, I took 20 mg of the famotidiine with two glasses of water.   (I'd eaten a large meal about two hours earlier.)  After taking the Pepcid, I waited an hour, then drank a glass of merlot fairly quickly.  I was ecstatic at first, because I looked pretty normal for a while.  Just faintly pink in the cheeks.  Usually, I turn red within fifteen seconds of my first sip.  But after about 20 minutes, the flush seemed to be coming back, and soon I was glowing at maximum intensity.  I tried popping another 20 mg of the famotidine, but I stayed red and glassy-eyed.

Second time, I upped the inital dosage to 40 mg, then stuck to the same procedure as the first experiment.  Same disappointing result, where the glow was just delayed for 20 minutes.

I'll try again in the near future with different alcohol types.  In about a month, I'll be going away to a place where the red wine will be flowing.  I was hoping that Pepcid would let me have a few glasses of rioja, but I guess I'll just hafta abstain ... as usual.

ASIDE:  One thing I've found is that VODKA mixed with something CITRUS-y plus SUGAR seriously minimizes the Asian flush.  No drugs involved whatsoever.  If I pace myself while I'm drinking lemon drops, vodka gimlets, or similar mixed drinks, then I barely turn red, especially if I eat something while I'm drinking.  This weekend, I had a few cocktails with "key lime" in the name ... it was vodka, peach schnappes, lime juice, and I just got a little pink; my eyes didn't turn glassy at all.  Weird, huh?  Amaratto sours, midori sours .... almost anything sour (except whiskey sours!) also seem to restrain the Asian flush somewhat.

The worst offenders at flushing up my skin are tequila, gin, beer, and wine, especially red wine.  I go radioactive-red when I drink those.  The red tends to last for 2-3 hours, regardless of number of drinks, i.e. whether I've had just one or as many as seven drinks.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Well I wouldn't drink without eating and I don't get how eating works into the picture if you're supposed to take pepcid AC on an empty stomach.  Should I eat dinner, wait some time (how long would this be?) before pepcide AC, then wait another 30 mins at least till drinking?  Or should I pop the pill on an empty stomach, eat later (again, how long with this be?) and then drink?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Cool, so sour stuff helps reduce the flush.  I'll try some other things out this weekend, I think we can cure this fawking thing.  I used to drink like a bottle of wine, it tasted so damn good.  The pounding and dizzyness only effects me if I don't drink for long periods of time.  We'll I'll do some test and post results. thanks a lot man.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Firstly, I will have to take back what I said about those New Zealand chemist websites - it seems that Pepzan has been discontinued in that country! :( Sorry guys.

Secondly - I'd like to share my awesome experience from the weekend. I went to a friend's cocktail party and I had a great time. I had 60mg famotidine about 2.5 hours before my first drink. I didn't have dinner - only nibbles throughout the night.

I had my first couple of drinks fairly slowly... probably averaged about 1 drink every 45 mins for the first 3 drinks.

* I started with a Sea Breeze at around 5pm - it went down very easily. A check in the mirror told me that the cool little pills were doing their job.
* Then a juice - I didn't want to run the risk of going red too quickly
* Then 2 rather strong Pina Coladas... still all good. I was feeling a little warm but nothing too bad. By the end of these I'm guessing it was around 7pm
* I think I had another juice. By this time I'm feeling just fine. Without the pills, I'd be beet red all over, my heart and head would be pounding and I'd be looking for somewhere to lie down!
* then another cocktail whose name escapes me, and a mojito
* Then a few more...
* Sips of water throughout the night
* At about 12pm me and my new buddies start with the shots - a B52 and a Black Magic (both yum!)
* We finished off with a bang of 5 shots in about 30-45 mins... 2x B52, 2x Black Magic and 1x Hawaiian Haze (yuk!)

I have to honestly say that I was amazed that I didn't go red at all... nor did I go majorly drunk! I was tipsy of course and didn't drive, but I was only tipsy and there was no hangover the next day! Blimin amazing!!
All up I think I had between 15-18 drinks/shots and I was only slightly rosy by the end of the night.

This has to be the best experience that I've had with Pepcid so far. Sometimes it works great sometimes it hardly works at all. I do think that the lack of a heavy meal and starting slowly helped in keeping the redness away.

Perhaps what Mistletoe says is right - spirits and juice things are better for us than wine... I didn't have any wine and most of my cocktails are the fruity ones with Vodka, Midori, Cointreau etc.

How was everyone else's weekends?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Well! I hate doing the predrink, but sometimes i have to do it and I come out fine all night long.  I don't want to take a nap when I pre-drink, but I get really bored and you know don't want to hear anything from the public, so I do pass out.  I don't know how my friend beat the thing, but he did! I don't know where he's at so I can't tell you how he did it. He just randomly drinks when he wants to and he's flush stuff dosen't come back at all. well im out

320

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Recently, I have been mixing both pepcid  ac and zantac taking 20 mg of pepcid ac and 150 mg of zantac.  I still turn red and feel the heat on my face but as the night progresses, it goes away.  i pregame before i go out to a party with vodka and after taking 2 shots, i get the blush but a couple hours later when i go to the party and start drinking beer, i feel no redness or heat.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I see some of you are still using the same technics to solve this problem. So I really have to ask how many of you are really serious enough to find a solution? I do apologize for my help is long over due,  I have been overwhelmed lately with work and family.  For those who are new. I'am a Research Assistant in Alcoholism for a company which I choose not to reveal. For the simple purpose of the company adhering to non-public exposure. Simple terms. My career in the company might become of question, if an investigation occurs from suspected information leakage.  Basicially the information gathered belongs to the company, and not to any personnel.  I have only done some research and testing dealing with Asian Flush. Each individual revealed more information than the test it self.  The company has strayed away from that research, also the reason why I choose to do it on my own time.
*THE GOAL:Equal opportunity! Wouldn't it sound great to be free! To be a non-flush victum.  This is the dream you reach for, so don't slip away from your dream just yet.  My goal is to have everyone of you free from Asian Flush. What is your goal?
*THE PROMISE:I promise to give all of you the best that I can do. Just don't give up on me!
*INFORMATION:-I believe all of you have more in common than you would acctually believe. With your identy safe; none of you should be ashamed of writing about your normal Friday or Saturday. So please I do ask all of you to write a typical Friday or Saturday. From waking up till your fast asleep.
-In a simple list form list what works least, to what works the best.(From what you have tried, make it short and sweet)
-I have brought up the discussion of everyone in here working toghter couple of times, and sometimes I do feel as if I have wasted my precious time. BUT! I'll stick with all of you till I have almost nothing left.

  I wrote everything basic as possible for everyone to understand.  I'm offering all of you a chance to rid yourself of heartache, embarassment, and denying yourself a fullfilled youth. Its a fact that a mass majority of people's nightlife evolve around drinking or partying, and the world is not going to change. Weigh what its worth to you, for some of you are destroying your bodies to obtain this dream.  Think about it. and speak out.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus-
I would like to hear what advice you may have to give.  I am a 20 yo male and get the asian flush slightly after one beer, and fully after 3.  I find that spicy foods make it worse and fruits and honey make it better.  I find that being unable to drink seriously limits my ability to socialize on weekends.  I think the ideal solution would be to have a pill with an acetaldehyde dehyrdogenase enzyme promoter or the enzyme itself.  But what are the other possibilites?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

There is a acetaldehyde dehyrdogenase enzyme pill(the pill wih the enzyme you need). The problem concerned with the pill is it can cause rapid blindness.  Speaking of pills some of you brought up the issue about "How they could have a pill that causes Asian Flush, but not have a pill to cure it."  The answer! The pill was made by accident in the 1940's, while scientist were trying to cure diseases.  To be honest there is no drug in the U.S. that can cure Asian Flush without very vicious side effects.

  Your best shot as of now (As in today), is RU-21 aka the hangover pill.  Order you RU-21 at http://www.911healthshop.com/ru21.html its cheap at that website. What I suggest you try for a self-experiment:Have a healthy intake of your B vitamns(the fruits, chicken, etc..), and give yourself about 30minutes to digest. Take the RU-21 pills, and start drinking. Because RU-21 is a "pill", it has a coated layer of chemical which dosn't desolve instantly. So some time maybe be needed to allow the pill to work.  All this preparation should take about 30min. It beats the 1-3 hour pre-drink meathod right.  If it does work for you, I suggest trying to do this process in less time. To test your time limit.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

How many of these pills do you take before?  How about during.  Do you know from experience?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Natifus wrote:

There is a acetaldehyde dehyrdogenase enzyme pill(the pill wih the enzyme you need). The problem concerned with the pill is it can cause rapid blindness.  Speaking of pills some of you brought up the issue about "How they could have a pill that causes Asian Flush, but not have a pill to cure it."  The answer! The pill was made by accident in the 1940's, while scientist were trying to cure diseases.  To be honest there is no drug in the U.S. that can cure Asian Flush without very vicious side effects.

  Your best shot as of now (As in today), is RU-21 aka the hangover pill.  Order you RU-21 at http://www.911healthshop.com/ru21.html its cheap at that website. What I suggest you try for a self-experiment:Have a healthy intake of your B vitamns(the fruits, chicken, etc..), and give yourself about 30minutes to digest. Take the RU-21 pills, and start drinking. Because RU-21 is a "pill", it has a coated layer of chemical which dosn't desolve instantly. So some time maybe be needed to allow the pill to work.  All this preparation should take about 30min. It beats the 1-3 hour pre-drink meathod right.  If it does work for you, I suggest trying to do this process in less time. To test your time limit.

i'm sorry but your very wrong here. Ru21 or cheerz does not work at all for the flush, it doesn't do anything, it's just a multi vitamin. been tried and tested, and i'm sure anyone with the flush will tell you the same.