1,001

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

^I hear you. I'm embarrassed to even go out. I've just gotten accustomed to telling people that I don't drink, even though I do love being drunk. It bothers me so much when coworkers / friends go out for a drink...... A drink, and I decline because of this condition. ugh.

Anyway, ever since those articles surfaced about the risks of throat cancer and such, I've been really weary of drinking and have practically stayed away from it entirely.

Anyone have any excuses that work well in social situations when getting pressured to have a drink? lol.

I'm only 24. :(

As always, Convivia needs to hurrrrrrrry.

1,002

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

i posted this in another thread, but here it is again- I've read that zantac (ranitidine) slows down alcohol dehydrogenase (ADH), but not pepcid (famotidine)-

http://www.annals.org/cgi/content/full/120/1/90

This suggests that zantac should be more effective at reducing acetaldehyde levels than pepcid.  Personally, I think Zantac works better, I feel less of a rapid heartrate and flushing.

1,003

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

^Interesting. I've never tried Zantac.... maybe I'll give it a whirl sometime.

For those of you that keep up with this thread...... to keep it semi active, let me ask you this. How do you guys handle situations where you're not prepared to drink. IE: you haven't taken your Pepcid or Zantac or whatever you take.

What do you do in a social situation like that where everyone wants you to drink, or everyone is drinking having a grand time?

Do you take the splurge and have a drink? Do you resist? What happens? How do you handle it?

1,004

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

just wondering if anyone has tried somac? its a 'proton pump inhibitor' and contains pantoprazole? does this work?

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I just found this forum tonight and wanted to share and see if anyone could help me....

I'm a 23 year old female with no asian decent at all (German, Irish and Spanish). I seem to be the only one out of my family who experiences this frustrating flushing issue. I developed this a few years ago. It had NEVER happened to be before that. Like some of you it doesn't happen all the time. Sometimes I go out and drink cocktails or beer and I'm completely fine (I prefer vodka and diet coke). Just last month I was at a friend's bachelorette party at a bunch of wineries which started at 11am and was terrified (because wine seems to induce it the most with me). To my surprise I only got a little blotchy on my jaw line and that's it.

Not only this but it seems there are certain things I (think I) can do to prevent it (not full proof but it's the only thing I've found thus far that helps, haven't tried the Pepcid or Zantac thing yet)

-Being in a very cool environment, it seems hot places or direct sunlight bring it on even worse/quicker
-working out a few hours before I drink
-staying away from wine

For awhile I thought it had something to do with my body temperature because I seem to flush on my face/neck/chest when I workout or am in hot environments while drinking (so much for summer bbq's) but then like some of you I get it if I eat something while drinking. (This doesn't work out so well when you go out to dinner with business clients who insist on you drinking). So then I'm either not drinking or not eating.

I'm basically really confused with what is going on. It even happens when I get embarrassed or emotional sometimes (with or without alcohol involved). With the eating thing I thought it might have to do with my blood sugar level?? Not sure why the workout out thing sometimes works, I thought maybe because I'm forcing my body to over heat it gets it all out and then won't come out later when I drink. Again this could all could just sound ridiculous but I'm pretty desperate. My boyfriend thinks I am huge pain because I need like hours notice before we go out due to my silly rituals of working out, eating in advance, planning the location (cool environments), etc. Geez I used to be so carefree and spontaneous!!

It also gets even worse when everyone questions me about being "sooo RED" or asking me whats wrong and insisting I have an allergy to some sort of food. I've had people try to give me asprin. Then due to the attention I get even more embarrassed and the red facial flushing blotches get even worse.

Sometimes it's not my whole face but weird blotches on my cheeks or jawline and other times it's my whole face :( Does anyone think this is "asian flush" or do I have some other issue. I went to my doctor and she tried to give me Propranolol. I took that a couple of times but it really didn't seem to work. I'm certain for a fact the alcohol does have something to do with it the times I get it while drinking because I am sometimes calm at home, not nervous at all, in a great mood, cool environment and then have 1-2 drinks and it comes on.

Any help or advice would be wonderful!!

PS. Also I feel like time of day or whether I'm tired contributes to it too. Sometimes when I drink in the mornings (like BBQ's or brunch) I'm ok. Then like around dinner or when I'm tired I feel like it is almost certain to come on if I have a drink.

1,006

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

i just bought some pepcid ac 10mg, how much should i take and how long before i drink?

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

When is Convivia going to be put on the market?  Im wondering if there could be a way to talk to someone on the phone that has information of this cure.  Anyone else desperate?

1,008

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Convivia is only in stage 2a. it still has to go through phase 2b refined formula and phase 3 final formulation before it goes up in front of the medical board to see if it will get passed. i have sent many an email to raptorpharma asking about progress but never get a reply. Last i heard was in November of last year and they were seeking partners in asia for the next phase. Im thinking maybe the global recession is slowing down such programs, but am forever hopeful that it may surface in a couple of years.

1,009

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

RedFace01 wrote:

I'm a 23 year old female with no asian decent at all (German, Irish and Spanish). I seem to be the only one out of my family who experiences this frustrating flushing issue. I developed this a few years ago. It had NEVER happened to be before that. Like some of you it doesn't happen all the time. Sometimes I go out and drink cocktails or beer and I'm completely fine (I prefer vodka and diet coke). Just last month I was at a friend's bachelorette party at a bunch of wineries which started at 11am and was terrified (because wine seems to induce it the most with me). To my surprise I only got a little blotchy on my jaw line and that's it.
For awhile I thought it had something to do with my body temperature because I seem to flush on my face/neck/chest when I workout or am in hot environments while drinking (so much for summer bbq's) but then like some of you I get it if I eat something while drinking. (This doesn't work out so well when you go out to dinner with business clients who insist on you drinking). So then I'm either not drinking or not eating.

The term "Asian" in "Asian Flush" is because of much higher percentage of Asians having this symptom.  One college classmate of mine is blond, blue eyes, pale skin and no visibly noticeable Asian background but he gets somewhat red around his cheeks and eyes every time he drinks.  So this gene is not 100% exclusive to Asians as I've seen more than one post like yours.

As for the intermittent occurrence, I'm not certain but it may have more to do with your heart rate if you flush during workout.  Alcohol consumption does increase the heart rate.  The rate is higher for some (w/ ALDH deficiency) than others.  For those with this deficiency, it will happen every time they drink enough of booze (one sip of beer won't do).

You may want to make an objective comparison on your own to see if there is consistency somewhere.  If there isn't, you may not have ALDH deficiency.

1,010

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Phantastic wrote:

When is Convivia going to be put on the market?  Im wondering if there could be a way to talk to someone on the phone that has information of this cure.  Anyone else desperate?

The contact info is here for you

Raptor Pharmaceuticals Corp.
9 Commercial Blvd., Suite 200
Novato, CA 94949

1-877-RAPTOR9/1-877-727-8679 (Toll-free in U.S. and Canada)
1-415-382-8111, ext. 200 (Local number)
1-415-382-1368 (Fax)

1,011 (edited by hi-fi 2009-06-11 06:29:00)

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

absucks wrote:

i posted this in another thread, but here it is again- I've read that zantac (ranitidine) slows down alcohol dehydrogenase (ADH), but not pepcid (famotidine)-

http://www.annals.org/cgi/content/full/120/1/90

This suggests that zantac should be more effective at reducing acetaldehyde levels than pepcid.  Personally, I think Zantac works better, I feel less of a rapid heartrate and flushing.

I tried Zantac (1 pill extra strength).  I wouldn't say it's night and day difference but it does make a difference in heart rate with flushing reduction at about the same as Pepcid (1 pill extra strength).  Overall I would say Zantac works better for me.

1,012

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I posted the result on Brewer's Yeast pills here.  http://echeng.com/asianblush/viewtopic. … 1537#p1537  Another method to reduce flush!

1,013

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

1 shot? and what if you have more alcohol? what sort of time period do the pills last for??

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I've been taking 10mg of the chewable Pepcid for about 3 years now and it seems to do the trick. It is still slightly noticeable (particularly in my eyes which go a bit red) but it's definately not as red on my face compared to not taking it. I might try increasing the dosage to 20mg and see if that reduces it even more.  It's become almost a habit now to make sure that I have some in my pocket before I go out. I don't tend to bother if I'm just drinking at home. Found this useful site which explains the problem and how to buy the solution: http://asian-flush.net/

1,015

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

schang1974 wrote:

I've been taking 10mg of the chewable Pepcid for about 3 years now and it seems to do the trick. It is still slightly noticeable (particularly in my eyes which go a bit red) but it's definately not as red on my face compared to not taking it. I might try increasing the dosage to 20mg and see if that reduces it even more.  It's become almost a habit now to make sure that I have some in my pocket before I go out. I don't tend to bother if I'm just drinking at home. Found this useful site which explains the problem and how to buy the solution: http://asian-flush.net/


How long does that one 10mg chewable last you and how long before you drink do you usually take it before your drink?

I use the pill form of the Pepcid and sometimes I find myself in the predicament of being out then going out for drinks later on. I was wondering if the chewable acts any faster than the pill form?

Thanks in advance.

1,016

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

schang1974 wrote:

Found this useful site which explains the problem and how to buy the solution: http://asian-flush.net/

I see a problem with that site's use of the term "definitive cure".  The use of H2 blockers is merely masking one aspect (visual) of the problem.  It does not cure the core problem (slow conversion of acetaldehyde to acetic acid) for those with this gene.  Using such term can be misleading and can give false sense of security on health issues to those who inherited this gene.  Unless there is a real cure that can tackle the core issue directly, those with ALDH2 deficiency gene are more prone to cancer if drank regularly (acetaldehyde is a carcinogen that can cause cancer).

They should change that term to something else.  :-(

1,017

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Any definitive stories on anyone having cancer / dying from cancer due to alcohol intake over time.... with the flush?

1,018 (edited by hi-fi 2009-07-19 17:49:09)

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

jasko wrote:

Any definitive stories on anyone having cancer / dying from cancer due to alcohol intake over time.... with the flush?

There is a higher risk of esophageal cancer on a person with ALDH2 deficiency gene that drank regularly. 
Here are some.
Link 1
Link 2
Link 3

There's more.  Try a search on "Asian flush cancer risk" on Google.

1,019

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Thanks for posting. I'm hating my life more and more.

:(

1,020

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

jasko wrote:

Thanks for posting. I'm hating my life more and more.

:(

Don't.  Nobody is born perfect.  We tend to recognize more of the negatives than positives.  Make the best of what you've got.

There are many famous achievers who didn't drink or quit drinking.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

So what works better...Pepcid or Zantac?

Pepcid Max works for me...i was wondering if Zantac max would have the same benefits?

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

As my user name suggests, my face looks like a baboon's butt after a drink, and about 2 years ago I started taking PEPCID TWO which is a UK product similar to pepcid AC because you can't buy pepcid AC here. Pepcid Two contains 10mg of the active ingredient Famotidine. It worked great for about a year, my face would only exhibit a mild pink glow opposed to the regular red hot beating of the sun. I don't drink very regularly. Maybe once or twice a month.

It was great. But about 9months ago, I realised that the pepcid two was becoming less effective. My face began turning redder and redder. Obviously not as red as if I hadn't taken pepcid two. I don't really understand why this has happened. It's as if my body has gotten used it and refuses to give me the same effects I experienced when I first started using it.

My question is, has anyone else experienced this? Or can anyone give me any information about why this might happen?

I am considering increasing the dosage to 20mg although the instructions say not to consume more than one in 24hrs! I have also tried zantac, but it doesn't seem to work for me.

Your responses are much appreciated.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

For me I do suffer from asian flush. Pretty badly too. But turing red isnt really a concern for me. Though it is embarassing I dont find it too troublesome. The thing that troubles me is not being able to drink. Yes i turn red as shttt, after 1 beer my face turns beat red, but the worst part is my heart pounds, i get killer head aches (after around 2-3 beers), i get extremly drousy, i feel sick(again after a few beers), and i get hot. I for the most part throw up after around 3-4 beers but usally dont make it that far. It is not a good feeling. Im sure some of you know the feeling im talking about. It seems like alot of people posting want to find a way to combat asian flush. But many if not most of you just want to get rid of the redness that occurs. But who cares if you can drink normally and get drunk like the majority of people.
So the point im trying to make is that I want to be able to drink. I want to be able to drink and have a good time. I want being drunk to be a good feeling like how all my friends describe. I throw up and feel completly out of it after just a few beers yet I feel like Im not actually drunk, most likely because I dont have enough alcohol in me. I am never like the drunk people screaming, running around, getting rowdy, or any of those things you associate with being drunk. Just out of it. So for me being drunk is not exactly a good feeling. In short i want to be able to get drunk not "asian flush drunk".  Im glad i found this disscusion : )
PS i just bought a package of 150mg zantech (no pepcid in Taiwan(here for a little bit but live in the states)) im exited to see the results!

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I hate that we even have to deal with this.  All I want is to be able to have a drink without taking stupid pills.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

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