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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I will in couple days. 

As for AF Reducer's results internally, I don't think it's as effective as Acetium because the heart rate went up sooner than trying Acetium. 

The bottom line is, until Convivia or Alda-1 is available to the public, I don't think there is a solid alternative, unfortunately.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Yeah, sounds good, Dalmore. I agree; hopefully Convivia makes it to the market sooner than later. Did the flushing eventually come back after a while when you were using AFR, or did it stay in check? Did you ever try taking 4 capsules of Acetium as well?

Sorry for the questions, just really curious.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Flushing came back little bit but didn't last long.   I was already sober at that point.
For me, 4 caps of Acetium didn't make any difference to 3 caps.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

After trying antacid and AF Reducer combo, I regret to say that it's not as effective as other combos I tried.  Externally, it works well but internally (which I consider more important) it's not helping much.  I won't be buying additional AF Reducer.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Happy holidays, everyone!

Sorry to hear, Dalmore. Is AF Reducer, however, the best solution you have tried for alleviating external symptoms? What has been the most effective combination of supplements that you have tried? Antacids and NoGlo worked well for me for a short time before my flushing recurred after a few test runs.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

For me, it was antacid and Acetium combo.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Thanks, Dalmore. Sounds like a good combo for both internal and external symptoms.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

hello and happy new year everybody :)
I was cruising around on Google and searched for the term "acetaldehyde dehydrogenase neutralize" and found this supplement that is made in japan (which is a place who has a lot of AF sufferers) . And they say it cures the symptoms, or reduces from hangovers. So i thought it might be quite interesting for you to read and maybe try it out.
the product is called "Hythiol-C". here is a link of their PDF file containing information.
http://www.ashburybio.com/hangover.pdf

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

So if Convivia or Alda-1 is released to the public does this mean that asian flush is permanently cured? 

Or is it like those other treatments like the AF Formula where you have to take it daily?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Jason1992 wrote:

the product is called "Hythiol-C".

I looked it up and noticed that it's been around for a while.  It's also marketed as skin condition supplement.

I have my doubts on its effectiveness against flushing.  If it is, why would Convivia set up markets in Japan and South Korea?

Their active ingredients show L-Cysteine, vitamin C and vitamin B5, which I happened to have some leftover from previous supplement shopping.  I'll try that combo and see what happens.

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

primehunta wrote:

So if Convivia or Alda-1 is released to the public does this mean that asian flush is permanently cured?

I would say it's more of "remedied" than "cured".  Curing ALDH2 enzyme deficiency would require altering people's existing DNA without damaging other DNA or organs, which I don't see happening in this century.  :(

Or is it like those other treatments like the AF Formula where you have to take it daily?

From what I've read, during Conviva testing on human, it was taken 30 minutes before drinking.  I would imagine that Alda-1 may be the same way.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I've tried using NAC, which is a derivative of the amino acid L-cysteine, and did not have great results. NAC by itself did not reduce flushing.

Has anyone tried using niacin in the form of brewer's yeast pills? Or brewer's yeast pills with Pepcid/Zantac? I know that there is already a thread on this, but I wanted to resurrect the topic here. I believe that niacin is supposed to activate the NAD enzyme that neutralizes acetaldehyde.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Dalmore wrote:
primehunta wrote:

So if Convivia or Alda-1 is released to the public does this mean that asian flush is permanently cured?

I would say it's more of "remedied" than "cured".  Curing ALDH2 enzyme deficiency would require altering people's existing DNA without damaging other DNA or organs, which I don't see happening in this century.  :(

Or is it like those other treatments like the AF Formula where you have to take it daily?

From what I've read, during Conviva testing on human, it was taken 30 minutes before drinking.  I would imagine that Alda-1 may be the same way.


hey Dalmore, I was going through the NoGlo thread and you said you had tried it before. Does it actually work? and how long did you take it for?

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

btw is there any research being done for a cure?

or will there never be one

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

So, I've been using Ranitidine actively for the past 8 months with great success. I still believe that theres a varying degree to how intense or severe the flushing reaction is because I can still, as long as I stick with beer/wine, get drunk without flushing and without taking ranitidine.

Since july I've been logging all my incidents, and logged every time I've been drinking to see if there's some sort of pattern to when I'm flushing, and when I'm not. And whether or not I've taken a pill or not. I've also been controlling my diet to see if it could have any effects, but it doesn't seem like it.

I have done some discoverys though. They may be random, but I've tested the "myths" atleast 10 times each to see if the results would differ:

1. Sugary booze is my worst enemy. Shots like jägermeister or turkish pepper, or mixed drinks with such types of booze are almost guaranteed to make my face glow. Jäger has a whopping 75g og sugar pr. liter, or 3 grams of pure sugar per shot. Anyway, Jäger has been the worst. Not a single time have I been able to drink this without flushing, unless I've been taking ranitidine.

2 Non-sugary boozes are howere fine, if the intake is slow and steady. For example Whisky (even bare!), mixed vodka-drinks, white rum drinks or gin drinks are fine. Black rum however is bad.

3. Dry sparkling wines like Cava or Prosecco (or even Champagne if the wallet allows it) are my new "go to" when drinking. Almost no sugar, the low alcohol % and the bubbles helping my stomach absorb the alcohol faster has made this my ultimate drinking partner. It's somewhat expensive in comparison to beer, but being able to drink a whole bottle (or even two!) without flushing and without any pills at all makes it a worthwile investment.

4. Beer is always a loose canon. I can have a couple at home without taking a pill, but if I'm going out or at a party I'll have to take a pill because I'll never know whether I'm going to flush or not.

I was also concerned that I had some sort of rosacea and visited a skin doctor last spring, but he couldn't find any evidence of any kind og skin-condition, but said that my AFR could be the cause of a "permanent" or long-lasting redness in the skin. However, after persistently taking ranitidine over the last 8 months, the redness (when not drinking) has almost vanished and my skin looks clean again.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Hey sofla,

Wow, thanks so much for your awesome post. It should be really helpful for a lot of people, as it is for me. And congratulations for finding out what works for you!

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

By the way, sofla,

Can you please outline your timeline while using ranitidine, as in how long you wait between taking the medication and drinking? Thanks!

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

I don't think that I can post links here, but there is a very interesting picture article drawn by a med school student at UCSF that explains the Asian flush in simple terminology as well as offers a remedy for the flush. This remedy is, of course, Pepcid, but the author also recommends taking Pepcid immediately before drinking to prevent the glow. It can be found by searching for "Medical Mythbusters Asian Glow."

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

the best explanation yet about the ALDH2 and the possible Alda 1 treatment;)
http://physrev.physiology.org/content/94/1/1
hope some of u can use this info;D

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Hi all, haven't posted for a few years here but thought i'd revisit a topic that was on one of the earlier pages of this thread, but didnt seem to garner much discussion.

It was to do with the use of asthma inhalers to open up your lungs a bit more to stop the heavy breathing.  Afterall, isn't it the fact that our heart is beating so fast that is causing all the blood to flow to our faces and turning us red? 
I am an asthma sufferer, and notice that after a vigourous aerobic workout, my face will be red, just like as if i had been drinking alcohol.

I know that a lot of professional boxers train breathing techniques so that they can use this method to slow their heart rates down in between rounds, hence giving them greater cardio later on in the fight.  I tried this the last time i was out drinking, i kinda just zoned out and just really focused on my slow breathing, in through the nose and out through the mouth, going against the grain of my fast beating heart, just relaxing and concentrating on bringing my heart rate down. it probably looked a bit weird to my friends, but i didn't seem to go as red as usual, if at all, since i wasnt getting any of the usual comments about it. 

So my question is, is this a genuine method, or did I just have a lucky night with the redness?  Can using an asthma inhaler, combined with actively controlling your breathing, actually reduce the redness due to a slower heart rate?

Thanks for any answers

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

crocop65 wrote:

So my question is, is this a genuine method, or did I just have a lucky night with the redness?  Can using an asthma inhaler, combined with actively controlling your breathing, actually reduce the redness due to a slower heart rate?

No.  It has to do with digesting process of alcohol and its byproduct called acetaldehyde.  Try Google search on "alcohol flush reaction".

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Thanks for the answer Dalmore.

Also, there was an article on Yahoo which I'm not allowed to post here.  It was basically about drinking without getting drunk, and the method was simply having a teaspoon of active yeast for every pint you drink.

"Dry active yeast has an enzyme in it called alcohol dehydrogenases (ADH). This enzyme has the ability to break down alcohol their constituent parts of carbon, hydrogen, and oxygen, which is basically what happens when it gets to your liver. By having the yeast already in your stomach, it starts breaking down before it gets to the blood stream."

Any truth to this?

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Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

crocop65 wrote:

and the method was simply having a teaspoon of active yeast for every pint you drink.

"Dry active yeast has an enzyme in it called alcohol dehydrogenases (ADH). This enzyme has the ability to break down alcohol their constituent parts of carbon, hydrogen, and oxygen, which is basically what happens when it gets to your liver. By having the yeast already in your stomach, it starts breaking down before it gets to the blood stream."

Any truth to this?

There used to be a thread here on Brewer's Yeast pills but looks like it's been deleted.  Anyway, I tried those pills (available at nutrition stores) but only helped tiny bit.  Practically it has no effect against alcohol flushing.

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Hey guys,
So I can conclude after 60 days of using AF Formula that it did not work for me, even in conjunction with Pepcid AC and NoGlo. Looking at the ingredient list, AF Formula seems to target the brain's responses to acetaldehyde accumulation, rather than targeting the root of the flushing problem.

Although they do not completely eliminate the flush, I will continue to use NoGlo and Pepcid AC because they seem to treat the root of the flush. NoGlo has alpha lipoic acid and NAC, which generate glutathione that binds to acetaldehyde to form harmless byproduct. Pepcid AC, of course, acts as a H2 inhibitor that counteracts inflammation caused by acidity.

Additionally, I've been occasionally using Acetium, which uses a special form of L-cysteine that only becomes active in the digestive tract, where the toxic and flush-inducing acetaldehyde accumulates. This supplement also appears to counteract the flush. And as Dalmore noted a while ago, the antacid and Acetium combo seems to work well. Acetium, however, is the most expensive of the supplements that I've used (except the AF Formula that I've found out doesn't work for me), running at $42 USD for 60 capsules. Not too bad, I guess, if you only take 2-4 capsules on weekend nights.

The next time I go out for drinks, I'll be experimenting with a new stack. As a frustrated, severe flusher who is slowly running out of college party nights, I've decided to cover all of my bases. In addition to 40-60 mg of Pepcid AC, 2 capsules of NoGlo and 2 capsules of Acetium, I'll use 10 mg of cetirizine (commonly known as Zyrtec, an H1 blocker) and 325 mg of aspirin approximately 1 hour before drinking. Cetirizine inhibits the binding of histamine, which causes vasodilation (hence, the rush of blood to the face), to the body's H1 receptors. Aspirin inhibits the release of prostagladins, such as PGE2, that also contribute to flushing. Ibuprofen might work too, in this case.

Be assured that I've taken both aspirin and cetirizine with alcohol before with mixed results and have turned out relatively fine, but these alone only counteract certain pathways of the flush reaction.

If anyone is interested in experimenting with this stack or already has, please comment and let us know about it. Since finals are next week, I'll be out of commission until the end of exams, but I'll keep you all posted on how it works for me. Doubtful it will, but I hope it does.

Take care everyone!

Re: H2 Blockers (Tagamet, Pepcid, Zantac, Axid)

Hey guys!

So I tried the Pepcid/Aspirin/Zyrtec combo. Seemed to work a little bit, then not so much at all. Don't think that I took the pills early enough though. I popped them right before drinking, and I forgot the Acetium and lost my NoGlo bottle. I still have some hope that it'll work, but we'll see. I'll keep you guys posted.