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Asian Flush / Asian Blush / Asian Glow Community
Discussion and anecdotes about the Asian Flush/Flush/Glow/Red Face (turning red when drinking alcohol), including using H2 blockers (e.g. Tagamet, Pepsid, Zantac) and other products to combat its effects. Hosted by Eric Cheng on http://echeng.com
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Jan 11, 2005: On December 3, 2003, I posted
a message in my web journal about the Asian Blush, which quickly resulted in over 100 very-informative comments. This forum is intended to be an information source for those of us looking for information about why we turn red when we drink alcohol.
April 25, 2006: For now, guests may post new messages. We've gotten some spam, so you now must be registered to post.
NOTE: Please do NOT treat information posted here as medical advice. However, once you've read these forums you'll probably want to get ahold of some Pepcid AC. Please support these forums and
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OCD wrote:I've come up with a theory that the reason we think it gets us more drunk when taking famotidine is that we are so impressed with the fact that we can drink more and not go red, we actually drink faster which we are not used to causing us to feel more drunk?
My theory anyway
its actually because the enzyme ADH is inhibited (ie doesnt work aswell and therefore cant break down the ethanol) therefore there is a build up of ethanol which causes the 'drunkness'. In this way H2 blockers dont help the cause of flushing (the acetaldehyde/ethanal) but slow down the rate at which it is made and gives our less efficient enzymes more time to break the stuff down to acetic acid. :)
Ethanol is the substance that makes you drunk. if one were to use an inhibitor such as Formepizole or 4-Methylpyrazole hydrochloride to inhibit the enzyme activity of ADH (alcohol dehydrogenase) would you not get drunk really fast but reduce the whole affect of asian flush? That is the basic concept behind using H-2 blockers as they inhbit the action of ADH. However Im unsure as to whether such drugs are available on the high street and what side affects they may have.
btw Formepizole and 4-Methylpyrazole hydrochloride are inhibitors used to inhbit ADH when someone has methanol poisoning. (methanol and ethanol are broken down by the same enzyme ADH thats why ethanol used to be used as a treatment for methanol poisoning.) sorry this might be gobbledy gook for some but any Medic students out there want to shed some light?
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