Asian Flush / Asian Blush / Asian Glow Community
Discussion and anecdotes about the Asian Flush/Flush/Glow/Red Face (turning red when drinking alcohol), including using H2 blockers (e.g. Tagamet, Pepsid, Zantac) and other products to combat its effects. Hosted by Eric Cheng on http://echeng.com
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Asian Flush / Asian Blush / Asian Glow Community → Posts by MTER
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It's sad news...but I am glad we have a general timeframe! Good work! Now we just wait I guess...
Still nothing. I email the guy almost monthly and he keeps saying as soon as they come up with a timeline/timeframe, they'll let me know. They couldn't even give me a ballpark...weeks, months, years... I feel like I should be searching for esophageal cancer treatments at this rate. How disappointing for them just to sit on a medication that has already reached stage 2 in the US.
Dalmore, Convivia and Alda-1 are similar. Convivia is essentially the missing enzyme in ALDH-2 deficient people that allow them to break down alcohol into acetate instead of letting it remain as acetaldehyde. Alda-1 is, however, "fixing" the malformed gene so that our body can naturally produce was Convivia substitutes.
So yes, it is working slightly different in the way it introduces the enzyme into our body. However, Alda-1 seems a lot further from ever becoming available than Convivia since Convivia is already approved in an intravenous form. In a way, I'm a little nervous about Alda-1 and being a human beta since it is essentially altering my body to produce a chemical versus just taking the chemical when I need it. I don't think Alda-1 has been used on humans at all...am I missing something?
Hey Chris, I was wondering where you got the information that Convivia is not viable. I believe they passed Phase 1 and Phase 2 of their clinical trials and my understanding was that they wanted to test the market in Taiwan, hence why it is currently not going through Phase 3 in the states. I don't have a pharmaceutical background but I didn't think we could allow patient trials for stage 1 and stage 2 if there is known harm to patients using the medication.
As for the compound you are working on, I am glad you are taking matters into your own hands and I wish you the best of luck. However, if you are working on an H2 drug, or one that is modeled off of H2 antagonists, how is that different than Pepcid AC? Isn't it doing the same thing in treating the neutralization of acids in the stomach? I didn't think it could neutralize and break down Acetaldehyde which is the dangerous part and the cause of the flushing.
Additionally, if you are focusing your efforts on the stomach, how will this new compound address 2nd-pass alcohol metabolism that is done in the liver?
I have contacted Raptor multiple times and finally moved onto contacting Uni-Pharma (weekly until I heard back).
On February 14th I received a reply from the Business Development Manager who vaguely said that the project is going smoothly, however there are no estimated timelines at this point.
Frustrating to say the least but at least I now have an actual email contact and not a general inquiry address/form.
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Asian Flush / Asian Blush / Asian Glow Community → Posts by MTER
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